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Cutaneous Rosai-Dorfman Disease Presented with a Solid Mass in the Thigh: A Case Report

Rosai-Dorfman disease (RDD) is a rare benign disorder of histiocytic origin It was first described by Rosai and Dorfman as sinus histiocytosis with massive lymphadenopathy in 1969. The disease mainly affects cervical lymph nodes and may express extranodal involvement. A purely cutaneous form of RDD has also been described. The etiology of the disease is unknown. Various mechanisms such as genetic, infectious, and inflammatory have been proposed. Various forms of treatment are suggested ranging from local steroids to surgical excision. We report the case of a young female who presented with a cutaneous lesion of the right thigh and was subsequently diagnosed with RDD involving the skin and the subcutaneous tissue.


Vouros Dimitrios and Toutouzas Konstantinos

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