Abstract

Background: The efficacy of single high dose buprenorphine on the improvement of heroin and cannabis craving and suicidal thoughts has not sufficiently been studied.

Objective: To examine the effects of high dose of buprenorphine on the reduction of cannabis and heroin craving and suicidal thoughts.

Discussion: This study illustrates that administration of only one dose 96 mg buprenorphine is quite successful for the improvement of heroin withdrawal symptoms, cannabis caving and suicidal thoughts. So, our finding could be an important addition to the literature.

Conclusion: Administration of 96 mg buprenorphine as a single dose only is as efficient as standard daily use for the improvement of heroin withdrawal symptoms. In addition, single high dose of buprenorphine is very useful for the speedy management of cannabis withdrawal craving and suicidal ideas.