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Abstract

Value of the TruGraf Blood Test as a Biomarker for Monitoring Renal Transplant Recipients

Kidney transplantation is the optimal treatment for many patients with end-stage kidney disease. The short-term outcomes of kidney transplantation have improved in the past few decades as a result of development of newer immunosuppressive drugs, more effective anti-microbial prophylaxis, and improved surgical techniques; however, long-term outcomes remain suboptimal. Routine posttransplant monitoring consists of the measurement of serum creatinine (SCr) and immunosuppressive drug levels. However, both are insensitive and non-specific markers of graft damage.


Author(s):

First MR, Rose S, Schieve C, Lee D, Lewis P, Pierry D, David J, McNulty M, Clark D, Weiss G, Kurian S, Whisenant T, Friedewald JJ and Abecassis MM



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